This page was last edited on 17 december 2019, at 15. Computational study of antimalarial pyrazole alkaloids from. Preliminary phytochemical analysis showed that the leaves and stem bark of newboudia aevis and the leaves and inflorescence of aspilia africana. Pharmacogenomics of cameroonian traditional herbal. Flowers are tubular, pink, come in bunches, attract butterflies and bees. Six pyrazole alkaloids of natural origin isolated from newbouldia laevis in dr congo that exhibit antimalarial activitynamely withasomnine, newbouldine, and their parahydroxy and methoxy derivativeswere investigated theoretically. Hepatoprotective, phytochemical and antioxidant properties of. The clusters of lavender flowers bloom winter and spring. It was filtered and the filtrate concentrated dried in. Blood profile of west african dwarf goats fed panicum maximum supplemented with newbouldia laevis leaves. Keywords zanthoxylum zanthoxyloides, newbouldia laevis, haemonchus contortus, plants. Development, in vitro and in vivo evaluations of novel lipid drug. Pdf uterine contractile effects of the aqueous and ethanol leaf.
Phytochemical studies and antidiabetic activities of. Newbouldia laevis, african border tree, akoko tree, newboldia. The effect of oral administration of aqueous extract of. Introduction newbouldia laevis family bignoniaceae is a nonleguminous, medium sized angiosperm, commonly called boundary tree planted as hedgerows and as a life fence, chieftaincy tree used in chieftaincy and traditional religious ceremonies. The aim of the present study was to evaluate the in vitro antioxidant and free radical scavenging capacity of bioactive metabolites present in newbouldia laevis leaf extract. Agents that stimulate uterine contraction are classified as oxytocics 2 and are employed clinically for the induction and augmentation of labour as well as in the management of the third. The use of plants to facilitate birth or to protect the young embryo appears to be a common practice among traditional healers. Newbouldia laevis african border tree freund flowering.
Antiinflammatory and analgesic effects of ethanolic leaf extract of newbouldia laevis p. Collection of leaves and roots of newbouldia laevis fresh leaves and roots of newbouldia laevis were collected in the month of march, 2015 from izzi in abakaliki local government of ebonyi state. Pharmacogenomics of cameroonian traditional herbal medicine. The rams were allotted to three treatment groups containing 8 animals per group, each group were drenched with. Usda, ars, germplasm resources information network. Effects of leaf and root extracts of newbouldia laevis on. Journal of medicinal plants studies medicine cam in both rural and urban areas across nigeria has increased, but there is a great concern for its safety, efficacy as well as control and this poses a great challenge for health authorities and the general public. Iita headquarters pmb 5320, oyo road, ibadan 200001, oyo state, nigeria. A careful blend of saturated evennumbered, unbranched, natural fatty acids, for example. Chemical constituents, the stereochemistry of 3hydroxy. The record derives from iplants data supplied on 20120323 which reports it as an accepted name record 317700 with original publication details. Boundary tree newbouldia laevis important information. Newbouldia in world checklist of selected plant families.
This plant is a popular and potent fertility herb that is used to treat all female reproductive disorders including infertility as the name implies. Agents that stimulate uterine contraction are classified as oxytocics and are employed clinically for the. To examine the phytochemical constituents and verify the ethnomedical claim of newbouldia laevis p. Anthelmintic properties of traditional african and caribbean. Hence, the effect of oral administration of aqueous extract of newbouldia laevis leaves for twenty one 21 days on reproductive hormones of albino male rats was investigated. Preparation of plant extracts the fresh leaves of newbouldia laevis were air dried for 7 days and ground into powdered form, 400g of each plant samples were extracted using 6000ml of 70% ethanol and shaken intermittently for 72 hours. Stem bark extract in a rat model article pdf available in pharmacognosy magazine 517. The pdf file you selected should load here if your web browser has a pdf. Newbouldia laevis leaves, stem bark and root bark chemical components were extracted. The extract revealed the presence of flavonoids, tannins, terpenes, steroidal and cardiac glycosides. Traditional medicine and the future of medicinal plants in. Onyekwelu of applied biology department, ebonyi state university, abakaliki.
Twelve male albino rats were grouped into three a, b and c of four 4 each. For more multimedia, look at newbouldia laevis on wikimedia commons. The plant has shiny dark green leaves and bears large showy terminal purple flowers. The nitro derivatives of withasomnine and parahydroxywithasomnine, which show enhanced antimalarial activity, were also studied in this manner. Mar 14, 2015 the aim of the present study was to evaluate the in vitro antioxidant and free radical scavenging capacity of bioactive metabolites present in newbouldia laevis leaf extract. Antiinflammatory, phytochemical and acute toxicity study of. Newbouldia laevis is one of such plants and its leaves are used in southeastern nigeria to hasten parturition and to expel the placenta after delivery. This article is a compilation of fertility herbs and their local names, alongside an interview with a traditional medicine practitioner. Beauv is a medicinal plant traditionally used to treat various diseases across african countries. Creative commons attributionnoncommercialsharealike 3. Oct 29, 2014 six pyrazole alkaloids of natural origin isolated from newbouldia laevis in dr congo that exhibit antimalarial activitynamely withasomnine, newbouldine, and their parahydroxy and methoxy derivativeswere investigated theoretically.
Newbouldia laevis methanolic extracts on three lifecycle stages of. Toxicological assessment of ethanolic extract of the leaves. Useful tropical plants database 2014 by ken fern, web interface by ajna fern with help from richard morris. It is a very popular plant in the african continent and is highly valuable due to its numerous immense benefits to human race. Chemical constituents of dorstenia picta and newbouldia laevis article in biochemical systematics and ecology 36. Tree bark, roots, leaves epilepsy, diabetes, convulsions, skin infections 32. The database and code is licensed under a creative commons attributionnoncommercialsharealike 3. Some other people from tlc same area use the leaf and inti0rescenc cf a. The hepatoprotective activity of the plant reported in this study would provide scientific evidence of its claimed medicinal properties. The original guide called pftek is an invention from psylocybe fanaticus pf, a scientist in growing fungi and spore seller. Hepatoprotective, phytochemical and antioxidant properties. Bauv used in the treatment of diabetes mellitus in nigeria bosha ja1, anaga ao2 and asuzu iu2 1department of veterinary physiology and pharmacology, university of agriculture, makurdi, benue state, nigeria 2department of veterinary physiology and pharmacology, university of nigeria, nsukka, enugu state, nigeria. Aduruku in hausa, ogirisi in igbo and akoko in yoruba languages hutchinson and dalziel, 1963 is a medium sized angiosperm which belongs to the bignoniaceae family. Among these, nine quinone derivatives 17, 12, one triterpeniod 8, and three steroids 911 were isolated.
In nigerian major languages it is called aduruku in hausa, ogirisi in igbo and akoko in yoruba 3. The major challenge in genotoxicity testing resides in developing methods that can reliably and. The methanolic leaf extract of newbouldia laevis was subjected to preliminary phytochemical screening and invitro antimicrobial tests. Pdf antinociceptive effects of newbouldia laevis p.
The plant is valued for many medicinal properties in various african tropical catalogues. Leaves are lush, tropical looking, dark red and waxy. In this study, the acute and subchronic toxicity profiles of the ethanolic extract of the leaves of n. Seeman ex bureau is a bignoniaceae widely distributed in usa, central africa and west africa. All plants, bloom seasons, flowering trees, medium trees, spring, winter by admin the place of origin for this medium evergreen tree is tropical africa. Ethnobotanical studies of port harcourt metropolis, nigeria. Uterine contractile effects of the aqueous and ethanol. Chromatographic and spectrophotometric methods were used in the study and modified where necessary in the study. This work is the first report combining a wholistic chemical study of all n.
Garden catalogs orisha exotic plants medicinal plants african fashion spirituality bloom gardens science. Newbouldia laevis in the germplasm resources information network grin, u. Antibacterial, antiinflammatory and antimalarial activities of some nigerian medicinal plants edited by j. The ibibio and efik people of nigeria regard the tree as a symbol of their deities thus they tend to place it in sacred places. Newbouldia laevis is a fastgrowing evergreen shrub or small tree. As a result, there is need to study the flower root of bark of newbouldia laevis, family. Jul 29, 2014 chemical constituents, the stereochemistry of 3hydroxy furonaphthoquinones from the root bark of newbouldia laevis seem bignoniaceae, and screening against onchocerca ochengi parasites authors kenneth o. Toxicological assessment of ethanolic extract of the.
Gcms, phytochemical and antimicrobial analysis of the leaf of. Files are available under licenses specified on their description page. Chemical constituents of dorstenia picta and newbouldia laevis. On oct 2, 2007, rareplantbroker from fort pierce, fl wrote. There still exist a large number of tropical trees with. One hundred and fifty structured questionnaires were administered, including oral interviews to herbal practitioners and users located at different parts of the city. Newbouldia laevis are widely reported to be used in the treatment of endemic. Treeto 15 m tall with pinnate leaves, the leaflets 4jugate, to 16. Some villages in ivory coast and gabon plant the tree near the tombs to act as a protective talisman. This page was last edited on 21 february 2016, at 12. Fertility herbs and their local names the fertile chick.
Toxicological survey of african medicinal plants various guidelines have been established to identify potential risk for carcinogenicity and heritable mutations 56,57. With the increasing population and high industrial activities, the use of newbouldia laevis as a medicine has also increased. Pdf phytochemical and antibacterial evaluations of the stem bark. Family compositae for wound dressing and earaches caused by inflammation of the car. Newbouldia laevis is commonly known as african border tree. Phytochemical and in vitro antimicrobial assay of the leaf.
Research article open access in vitro newbouldia laevis extract. This pretty fast growing mediumsize tree is close related to popular tabebuias. Pdf based on traditional reports, the aqueous and ethanol extracts of the leaves of n. The antimicrobial activity of the plant extract was assayed by the agar plate disc diffusion and nutrient broth dilution techniques.
Materials and methods chemicals all chemicals used were of analytical grade. The genus newbouldia is in the family bignoniaceae in the major group angiosperms flowering plants. Phytochemical and antimicrobial analysis of the leaf of newbouldia laevis. Analgesic and antiinflammatory screening of newbouldia. Antiinflammatory, phytochemical and acute toxicity study. It only reaches a height of 3 8 metres in the west of its range, but can attain a height of up to 20 metres in the east 200. Newbouldia laevis commonly called african border tree or boundary tree is known locally as aduruku in hausa, ogirisi in igbo and akoko in yoruba languages of northern, eastern and western nigeria, respectively.
Through bioassayguided fractionation, compounds 1 were isolated from the ch 2 cl 2 meoh 1. Bignoniaceae african border tree, akoko tree, newboldia origin. Research article open access in vitro newbouldia laevis. In vitro antioxidant capacity and free radical scavenging. It has earned its common name, the boundary tree, due to the fact that it is planted as a living fence in its native habitat to mark property boundaries.
Uterine contractile effects of the aqueous and ethanol leaf. Congolese newbouldia laevis revealed the absence of flavonoids, saponnins, quinonones, terpenes and steroids gafner et al. Chemical characterization and biological activities of. Computational study of antimalarial pyrazole alkaloids. Poisonous mushrooms edible mushrooms stuffed mushrooms types of slime slime mould mushroom fungi unusual plants shade plants forests. Synonymic checklists of the vascular plants of the world 2019. Apr 19, 2019 fertility plant or indian cork tree newbouldia laevis. Newbouldia laevis has different symbols and meanings to different countries for example. Newbouldia laevis family bignoniaceae as an external antiseptic for wound dressing. Newbouldia laevis african border tree all plants, bloom seasons, flowering trees, medium trees, spring, winter by admin the place of origin for this medium evergreen tree is tropical africa. It is a familiar livefence and boundary tree throughout its. Newbouldia laevis, african border tree, akoko tree.
Newbouldia laevis is usually grown as an ornamental tree and planted by cuttings. In nigeria, the plant has been found to be effective in the treatment of elephantiasis, dysentery, rheumatic swellings, syphilis, constipation, pile and as a vermifuge to round worms usman and osuji, 2007. In nigeria the leaves of the plant are used in the treatment of convulsions, diabetes, and different bacterial infections. A shrub or small tree reaching to 78 m high in the west senegal, 26 to 20 m in the east nigeria, 21 of the region, and to 2. Department of agriculture agricultural research service.
Introduction scientific validations are being made globally to get evidences for traditionally used herbal plants. Hepatoprotective effect, newbouldia laevies, antioxidant properties, lipid peroxidation. A total of twenty four growing west african dwarf rams between 1215 months old and of balanced weight were used for the experiment. Chukwujekwu, 1 j van staden, 1 email protected p smith, 2 1 research centre for plant growth and development, school of biological and conservation science, university of kwazulunatal pietermaritzburg, private bag x01, scottsville 3209, south africa research centre for. Cardioprotective effect of leaf and root extracts of newbouldia laevis against carbon tetrachloride inducedcardiotoxicity in albino rats. This study was conducted to assess the effect of newbouldia laevis leaf extract on growth performance and faecal egg count of west african dwarf sheep. The board of trustees of the royal botanic gardens, kew. Newbouldia laevis is a sunloving, fastgrowing, droughttolerant species from west tropical africa. It is a familiar livefence and boundary tree throughout its distribution. From 148 phytochemically investigated plants used in various traditional healing in cameroon, it can be observed that 116 of the 148 78.
Involvement of tannins and flavonoids in the in vitro effects of newbouldia laevis and zanthoxylum zanthoxyloides extracts on the. Biochemical and haematological effects of the leaf extract. Newbouldia laevis boundary tree african border tree akoko. Differential constituents in roots, stems and leaves of newbouldia. Two 2 grammes of newbouldia laevis leaf extract was dissolved in 40 ml of distilled water to obtain a concentration of 50 mgml and was used to test for starch, carbohydrates, alkaloids, saponins, flavonoids, polyuronoids, tannins and sterolsterpenes. Pdf antiinflammatory and analgesic effects of ethanolic. Pendejera tambien es llamada o conocida como hierba bruja. See status, confidence level, source for definitions. The stereochemistry of 3hydroxy furonaphthoquinones. All structured data from the file and property namespaces is available under the creative commons cc0 license. Newbouldia laevis is native to tropical africa and grows from guinea savannahs to dense forests arbonnier, 2004.
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